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Depletion of White Adipose Tissue in Cancer Cachexia Syndrome Is Associated with Inflammatory Signaling and Disrupted Circadian Regulation
Involuntary weight loss in patients with cancer is the hallmark of cancer cachexia. The etiology of cachexia is multifactorial involving loss of skeletal muscle and adipose tissue associated with high systemic levels of acute phase proteins and inflammatory cytokines. While muscle wasting overtly im...
Autores principales: | Tsoli, Maria, Schweiger, Martina, Vanniasinghe, Anne S., Painter, Arran, Zechner, Rudolf, Clarke, Stephen, Robertson, Graham |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965507/ https://www.ncbi.nlm.nih.gov/pubmed/24667661 http://dx.doi.org/10.1371/journal.pone.0092966 |
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