Granulocytes Affect Double-Strand Break Repair Assays in Primary Human Lymphocytes

Patients who develop therapy-related myelodysplasia/acute myeloid leukemia after autologous-hematopoietic stem cell (aHCT) transplant show lower expression levels of DNA repair genes in their pre-aHCT CD34(+) cells. To investigate whether this leads to functional differences in DNA repair abilities...

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Detalles Bibliográficos
Autores principales: Lacoste, Sandrine, Bhatia, Ravi, Bhatia, Smita, O'Connor, Timothy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965556/
https://www.ncbi.nlm.nih.gov/pubmed/24667872
http://dx.doi.org/10.1371/journal.pone.0093185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965556/
https://www.ncbi.nlm.nih.gov/pubmed/24667872
http://dx.doi.org/10.1371/journal.pone.0093185

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