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Granulocytes Affect Double-Strand Break Repair Assays in Primary Human Lymphocytes

Patients who develop therapy-related myelodysplasia/acute myeloid leukemia after autologous-hematopoietic stem cell (aHCT) transplant show lower expression levels of DNA repair genes in their pre-aHCT CD34(+) cells. To investigate whether this leads to functional differences in DNA repair abilities...

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Detalles Bibliográficos
Autores principales:	Lacoste, Sandrine, Bhatia, Ravi, Bhatia, Smita, O'Connor, Timothy R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965556/ https://www.ncbi.nlm.nih.gov/pubmed/24667872 http://dx.doi.org/10.1371/journal.pone.0093185

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