Role of the Lipoxygenase Pathway in RSV-induced Alternatively Activated Macrophages Leading to Resolution of Lung Pathology

Resolution of severe RSV-induced bronchiolitis is mediated by alternatively activated macrophages (AA-Mϕ) that counteract cyclooxygenase (COX)-2-induced lung pathology. Herein, we report that RSV infection of 5-lipoxygenase (LO)(−/−) and 15-LO(−/−) macrophages or mice failed to elicit AA-Mϕ differen...

Descripción completa

Detalles Bibliográficos
Autores principales: Shirey, Kari Ann, Lai, Wendy, Pletneva, Lioubov M., Karp, Christopher L., Divanovic, Senad, Blanco, Jorge C. G., Vogel, Stefanie N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965659/
https://www.ncbi.nlm.nih.gov/pubmed/24064666
http://dx.doi.org/10.1038/mi.2013.71

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965659/
https://www.ncbi.nlm.nih.gov/pubmed/24064666
http://dx.doi.org/10.1038/mi.2013.71

Ejemplares similares