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Initiation of Meiotic Recombination in Mammals

Meiotic recombination is initiated by the induction of programmed DNA double strand breaks (DSBs). DSB repair promotes homologous interactions and pairing and leads to the formation of crossovers (COs), which are required for the proper reductional segregation at the first meiotic division. In mamma...

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Detalles Bibliográficos
Autores principales: Kumar, Rajeev, de Massy, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966222/
https://www.ncbi.nlm.nih.gov/pubmed/24710101
http://dx.doi.org/10.3390/genes1030521