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Diet‐induced obesity in mice reduces placental efficiency and inhibits placental mTOR signaling

As in humans, obesity during pregnancy in mice results in elevated maternal insulin levels and metabolic programming of offspring. mTOR signaling regulates amino acid transport and may function as a placental nutrient sensor. Because obesity is a condition with increased nutrient availability, we hy...

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Detalles Bibliográficos
Autores principales: Lager, Susanne, Samulesson, Anne‐Maj, Taylor, Paul D., Poston, Lucilla, Powell, Theresa L., Jansson, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966251/
https://www.ncbi.nlm.nih.gov/pubmed/24744907
http://dx.doi.org/10.1002/phy2.242