Elovl2 ablation demonstrates that systemic DHA is endogenously produced and is essential for lipid homeostasis in mice

The potential role of endogenously synthesized PUFAs is a highly overlooked area. Elongation of very long-chain fatty acids (ELOVLs) in mammals is catalyzed by the ELOVL enzymes to which the PUFA elongase ELOVL2 belongs. To determine its in vivo function, we have investigated how ablation of ELOVL2,...

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Detalles Bibliográficos
Autores principales: Pauter, Anna M., Olsson, Petter, Asadi, Abolfazl, Herslöf, Bengt, Csikasz, Robert I., Zadravec, Damir, Jacobsson, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966705/
https://www.ncbi.nlm.nih.gov/pubmed/24489111
http://dx.doi.org/10.1194/jlr.M046151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966705/
https://www.ncbi.nlm.nih.gov/pubmed/24489111
http://dx.doi.org/10.1194/jlr.M046151

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