Impact of intracellular domain flexibility upon properties of activated human 5-HT(3) receptors*

BACKGROUND AND PURPOSE: It has been proposed that arginine residues lining the intracellular portals of the homomeric 5-HT(3)A receptor cause electrostatic repulsion of cation flow, accounting for a single-channel conductance substantially lower than that of the 5-HT(3)AB heteromer. However, compari...

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Detalles Bibliográficos
Autores principales: Kozuska, J L, Paulsen, I M, Belfield, W J, Martin, I L, Cole, D J, Holt, A, Dunn, S M J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966743/
https://www.ncbi.nlm.nih.gov/pubmed/24283776
http://dx.doi.org/10.1111/bph.12536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966743/
https://www.ncbi.nlm.nih.gov/pubmed/24283776
http://dx.doi.org/10.1111/bph.12536

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