ALDH Maintains the Stemness of Lung Adenoma Stem Cells by Suppressing the Notch/CDK2/CCNE Pathway

OBJECTIVE: To evaluate the expression of ALDH1A1 in lung adenoma stem cells (LASCs) and maintenance of their stemness through the Notch pathway. METHODS: LASCs (A549s) were isolated from lung adenoma cells (A549) and identified by their coexpression of CD133 and CD326 and their capacity formulti-dir...

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Detalles Bibliográficos
Autores principales: Li, Zhongjun, Xiang, Yang, Xiang, Lixin, Xiao, Yanni, Li, Fengjie, Hao, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966794/
https://www.ncbi.nlm.nih.gov/pubmed/24671051
http://dx.doi.org/10.1371/journal.pone.0092669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966794/
https://www.ncbi.nlm.nih.gov/pubmed/24671051
http://dx.doi.org/10.1371/journal.pone.0092669

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