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DNA Compaction Induced by a Cationic Polymer or Surfactant Impact Gene Expression and DNA Degradation

There is an increasing interest in achieving gene regulation in biotechnological and biomedical applications by using synthetic DNA-binding agents. Most studies have so far focused on synthetic sequence-specific DNA-binding agents. Such approaches are relatively complicated and cost intensive and th...

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Detalles Bibliográficos
Autores principales: Ainalem, Marie-Louise, Bartles, Andrew, Muck, Joscha, Dias, Rita S., Carnerup, Anna M., Zink, Daniele, Nylander, Tommy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966812/
https://www.ncbi.nlm.nih.gov/pubmed/24671109
http://dx.doi.org/10.1371/journal.pone.0092692