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Solid Bioneedle-Delivered Influenza Vaccines Are Highly Thermostable and Induce Both Humoral and Cellular Immune Responses

The potential of bioneedles to deliver influenza vaccines was investigated. Four influenza vaccine formulations were screened to determine the optimal formulation for use with bioneedles. The stability of the formulations after freeze-drying was checked to predict the stability of the influenza vacc...

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Detalles Bibliográficos
Autores principales: Soema, Peter C., Willems, Geert-Jan, van Twillert, Klaas, van de Wijdeven, Gijsbert, Boog, Claire J., Kersten, Gideon F. A., Amorij, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966824/
https://www.ncbi.nlm.nih.gov/pubmed/24671048
http://dx.doi.org/10.1371/journal.pone.0092806