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Solid Bioneedle-Delivered Influenza Vaccines Are Highly Thermostable and Induce Both Humoral and Cellular Immune Responses
The potential of bioneedles to deliver influenza vaccines was investigated. Four influenza vaccine formulations were screened to determine the optimal formulation for use with bioneedles. The stability of the formulations after freeze-drying was checked to predict the stability of the influenza vacc...
Autores principales: | Soema, Peter C., Willems, Geert-Jan, van Twillert, Klaas, van de Wijdeven, Gijsbert, Boog, Claire J., Kersten, Gideon F. A., Amorij, Jean-Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966824/ https://www.ncbi.nlm.nih.gov/pubmed/24671048 http://dx.doi.org/10.1371/journal.pone.0092806 |
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