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Overexpression of S100A7 Protects LPS-Induced Mitochondrial Dysfunction and Stimulates IL-6 and IL-8 in HaCaT Cells

BACKGROUND: S100A7 (or psoriasin) is distributed in the cytoplasm of keratinocytes of normal human epidermis, and it is overexpressed in many epidermal inflammatory diseases. Lipopolysaccharide (LPS) induces mitochondrial function changes, which play important roles in multiple cellular mechanisms i...

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Detalles Bibliográficos
Autores principales: Sun, Wenyan, Zheng, Yan, Lu, Zhuoyang, Cui, Yang, Tian, Qiong, Xiao, Shengxiang, Liu, Feng, Liu, Jiankang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966836/
https://www.ncbi.nlm.nih.gov/pubmed/24671027
http://dx.doi.org/10.1371/journal.pone.0092927