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Redistribution of Flexibility in Stabilizing Antibody Fragment Mutants Follows Le Châtelier’s Principle

Le Châtelier’s principle is the cornerstone of our understanding of chemical equilibria. When a system at equilibrium undergoes a change in concentration or thermodynamic state (i.e., temperature, pressure, etc.), La Châtelier’s principle states that an equilibrium shift will occur to offset the per...

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Detalles Bibliográficos
Autores principales: Li, Tong, Tracka, Malgorzata B., Uddin, Shahid, Casas-Finet, Jose, Jacobs, Donald J., Livesay, Dennis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966838/
https://www.ncbi.nlm.nih.gov/pubmed/24671209
http://dx.doi.org/10.1371/journal.pone.0092870