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Redistribution of Flexibility in Stabilizing Antibody Fragment Mutants Follows Le Châtelier’s Principle
Le Châtelier’s principle is the cornerstone of our understanding of chemical equilibria. When a system at equilibrium undergoes a change in concentration or thermodynamic state (i.e., temperature, pressure, etc.), La Châtelier’s principle states that an equilibrium shift will occur to offset the per...
Autores principales: | Li, Tong, Tracka, Malgorzata B., Uddin, Shahid, Casas-Finet, Jose, Jacobs, Donald J., Livesay, Dennis R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966838/ https://www.ncbi.nlm.nih.gov/pubmed/24671209 http://dx.doi.org/10.1371/journal.pone.0092870 |
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