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Distinct Pathways of ERK1/2 Activation by Hydroxy-Carboxylic Acid Receptor-1
Mechanistic investigations have shown that, upon agonist activation, hydroxy-carboxylic acid receptor-1(HCA(1)) couples to a G(i) protein and inhibits adenylate cyclase activity, leading to inhibition of liberation of free fatty acid. However, the underlying molecular mechanisms for HCA(1) signaling...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966839/ https://www.ncbi.nlm.nih.gov/pubmed/24671202 http://dx.doi.org/10.1371/journal.pone.0093041 |