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Distinct Pathways of ERK1/2 Activation by Hydroxy-Carboxylic Acid Receptor-1

Mechanistic investigations have shown that, upon agonist activation, hydroxy-carboxylic acid receptor-1(HCA(1)) couples to a G(i) protein and inhibits adenylate cyclase activity, leading to inhibition of liberation of free fatty acid. However, the underlying molecular mechanisms for HCA(1) signaling...

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Detalles Bibliográficos
Autores principales:	Li, Guo, Wang, Hui-qian, Wang, Li-hui, Chen, Ru-ping, Liu, Jun-ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966839/ https://www.ncbi.nlm.nih.gov/pubmed/24671202 http://dx.doi.org/10.1371/journal.pone.0093041

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