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Beta-Actin Deficiency with Oxidative Posttranslational Modifications in Rett Syndrome Erythrocytes: Insights into an Altered Cytoskeletal Organization

Beta-actin, a critical player in cellular functions ranging from cell motility and the maintenance of cell shape to transcription regulation, was evaluated in the erythrocyte membranes from patients with typical Rett syndrome (RTT) and methyl CpG binding protein 2 (MECP2) gene mutations. RTT, affect...

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Detalles Bibliográficos
Autores principales: Cortelazzo, Alessio, De Felice, Claudio, Pecorelli, Alessandra, Belmonte, Giuseppe, Signorini, Cinzia, Leoncini, Silvia, Zollo, Gloria, Capone, Antonietta, Giovampaola, Cinzia Della, Sticozzi, Claudia, Valacchi, Giuseppe, Ciccoli, Lucia, Guerranti, Roberto, Hayek, Joussef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966888/
https://www.ncbi.nlm.nih.gov/pubmed/24671107
http://dx.doi.org/10.1371/journal.pone.0093181