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Beta-Actin Deficiency with Oxidative Posttranslational Modifications in Rett Syndrome Erythrocytes: Insights into an Altered Cytoskeletal Organization
Beta-actin, a critical player in cellular functions ranging from cell motility and the maintenance of cell shape to transcription regulation, was evaluated in the erythrocyte membranes from patients with typical Rett syndrome (RTT) and methyl CpG binding protein 2 (MECP2) gene mutations. RTT, affect...
Autores principales: | Cortelazzo, Alessio, De Felice, Claudio, Pecorelli, Alessandra, Belmonte, Giuseppe, Signorini, Cinzia, Leoncini, Silvia, Zollo, Gloria, Capone, Antonietta, Giovampaola, Cinzia Della, Sticozzi, Claudia, Valacchi, Giuseppe, Ciccoli, Lucia, Guerranti, Roberto, Hayek, Joussef |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966888/ https://www.ncbi.nlm.nih.gov/pubmed/24671107 http://dx.doi.org/10.1371/journal.pone.0093181 |
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