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ERK and AKT signaling cooperate to translationally regulate survivin expression for metastatic progression of colorectal cancer
The MEK/ERK and PI3K/AKT pathways are often concurrently activated by separate genetic alterations in colorectal cancer (CRC), which is associated with CRC progression and poor survival. However, how activating both pathways is required for CRC metastatic progression remains unclear. Our recent stud...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966979/ https://www.ncbi.nlm.nih.gov/pubmed/23624914 http://dx.doi.org/10.1038/onc.2013.122 |