Cargando…

ERK and AKT signaling cooperate to translationally regulate survivin expression for metastatic progression of colorectal cancer

The MEK/ERK and PI3K/AKT pathways are often concurrently activated by separate genetic alterations in colorectal cancer (CRC), which is associated with CRC progression and poor survival. However, how activating both pathways is required for CRC metastatic progression remains unclear. Our recent stud...

Descripción completa

Detalles Bibliográficos
Autores principales: Ye, Qing, Cai, Weijia, Zheng, Yongbin, Evers, B. Mark, She, Qing-Bai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966979/
https://www.ncbi.nlm.nih.gov/pubmed/23624914
http://dx.doi.org/10.1038/onc.2013.122