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Molecular basis underlying histone H3 lysine–arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1

Histone modification patterns and their combinatorial readout have emerged as a fundamental mechanism for epigenetic regulation. Here we characterized Spindlin1 as a histone effector that senses a cis-tail histone H3 methylation pattern involving trimethyllysine 4 (H3K4me3) and asymmetric dimethylar...

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Detalles Bibliográficos
Autores principales: Su, Xiaonan, Zhu, Guixin, Ding, Xiaozhe, Lee, Shirley Y., Dou, Yali, Zhu, Bing, Wu, Wei, Li, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967050/
https://www.ncbi.nlm.nih.gov/pubmed/24589551
http://dx.doi.org/10.1101/gad.233239.113