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Rbfox2 controls autoregulation in RNA-binding protein networks

The tight regulation of splicing networks is critical for organismal development. To maintain robust splicing patterns, many splicing factors autoregulate their expression through alternative splicing-coupled nonsense-mediated decay (AS-NMD). However, as negative autoregulation results in a self-lim...

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Detalles Bibliográficos
Autores principales: Jangi, Mohini, Boutz, Paul L., Paul, Prakriti, Sharp, Phillip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967051/
https://www.ncbi.nlm.nih.gov/pubmed/24637117
http://dx.doi.org/10.1101/gad.235770.113