p53-dependent Fas expression is critical for Ginsenoside Rh2 triggered caspase-8 activation in HeLa cells

We have recently reported that Ginsenoside Rh2 (G-Rh2) induces the activation of two initiator caspases, caspase-8 and caspase-9 in human cancer cells. However, the molecular mechanism of its death-inducing function remains unclear. Here we show that G-Rh2 stimulated the activation of both caspase-8...

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Detalles Bibliográficos
Autores principales: Guo, Xiao-Xi, Li, Yang, Sun, Chao, Jiang, Dan, Lin, Ying-Jia, Jin, Feng-Xie, Lee, Seung-Ki, Jin, Ying-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967063/
https://www.ncbi.nlm.nih.gov/pubmed/24622841
http://dx.doi.org/10.1007/s13238-014-0027-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967063/
https://www.ncbi.nlm.nih.gov/pubmed/24622841
http://dx.doi.org/10.1007/s13238-014-0027-2

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