Cargando…
p53-dependent Fas expression is critical for Ginsenoside Rh2 triggered caspase-8 activation in HeLa cells
We have recently reported that Ginsenoside Rh2 (G-Rh2) induces the activation of two initiator caspases, caspase-8 and caspase-9 in human cancer cells. However, the molecular mechanism of its death-inducing function remains unclear. Here we show that G-Rh2 stimulated the activation of both caspase-8...
Autores principales: | Guo, Xiao-Xi, Li, Yang, Sun, Chao, Jiang, Dan, Lin, Ying-Jia, Jin, Feng-Xie, Lee, Seung-Ki, Jin, Ying-Hua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967063/ https://www.ncbi.nlm.nih.gov/pubmed/24622841 http://dx.doi.org/10.1007/s13238-014-0027-2 |
Ejemplares similares
-
Ginsenoside Rh2 Induces Human Hepatoma Cell Apoptosis via Bax/Bak Triggered Cytochrome C Release and Caspase-9/Caspase-8 Activation
por: Guo, Xiao-Xi, et al.
Publicado: (2012) -
Ginsenoside Rh2 inhibits HeLa cell energy metabolism and induces apoptosis by upregulating voltage-dependent anion channel 1
por: Liu, Ying, et al.
Publicado: (2020) -
Ginsenoside Rh2 Induces HeLa Apoptosis through Upregulating Endoplasmic Reticulum Stress-Related and Downstream Apoptotic Gene Expression
por: Liu, Ying, et al.
Publicado: (2022) -
Cleavage of Cdc6 by caspase-3 promotes ATM/ATR kinase–mediated apoptosis of HeLa cells
por: Yim, Hyungshin, et al.
Publicado: (2006) -
Low concentrations of doxycycline attenuates FasL-induced apoptosis in HeLa cells
por: Yoon, Jung Mi, et al.
Publicado: (2015)