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Pediatric Dosing and Body Size in Biotherapeutics
Although pediatric doses for biotherapeutics are often based on patients' body weight (mg/kg) or body surface area (mg/m(2)), linear body size dose adjustment is highly empirical. Growth and maturity are also important factors that affect the absorption, distribution, metabolism and excretion (...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967145/ https://www.ncbi.nlm.nih.gov/pubmed/27721364 http://dx.doi.org/10.3390/pharmaceutics2040389 |