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Endodermal differentiation of human pluripotent stem cells to insulin-producing cells in 3D culture

Insulin-producing cells (IPCs) derived from human pluripotent stem cells (hPSCs) may be useful in cell therapy and drug discovery for diabetes. Here, we examined various growth factors and small molecules including those previously reported to develop a robust differentiation method for induction of...

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Detalles Bibliográficos
Autores principales: Takeuchi, Hiroki, Nakatsuji, Norio, Suemori, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967149/
https://www.ncbi.nlm.nih.gov/pubmed/24671046
http://dx.doi.org/10.1038/srep04488