Chemoinformatic Analysis as a Tool for Prioritization of Trypanocidal Marine Derived Lead Compounds

Marine trypanocidal natural products are, most often, reported with trypanocidal activity and selectivity against human cell lines. The triaging of hits requires a consideration of chemical tractability for drug development. We utilized a combined Lipinski’s rule-of-five, chemical clustering and Che...

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Detalles Bibliográficos
Autores principales: Feng, Yunjiang, Campitelli, Marc, Davis, Rohan A., Quinn, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967203/
https://www.ncbi.nlm.nih.gov/pubmed/24599097
http://dx.doi.org/10.3390/md12031169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967203/
https://www.ncbi.nlm.nih.gov/pubmed/24599097
http://dx.doi.org/10.3390/md12031169

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