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CS5931, a Novel Polypeptide in Ciona savignyi, Represses Angiogenesis via Inhibiting Vascular Endothelial Growth Factor (VEGF) and Matrix Metalloproteinases (MMPs)

CS5931 is a novel polypeptide from Ciona savignyi with anticancer activities. Previous study in our laboratory has shown that CS5931 can induce cell death via mitochondrial apoptotic pathway. In the present study, we found that the polypeptide could inhibit angiogenesis both in vitro and in vivo. CS...

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Detalles Bibliográficos
Autores principales: Liu, Ge, Liu, Ming, Wei, Jianteng, Huang, Haijuan, Zhang, Yuyan, Zhao, Jin, Xiao, Lin, Wu, Ning, Zheng, Lanhong, Lin, Xiukun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967225/
https://www.ncbi.nlm.nih.gov/pubmed/24633253
http://dx.doi.org/10.3390/md12031530