Three New and Eleven Known Unusual C25 Steroids: Activated Production of Silent Metabolites in a Marine-Derived Fungus by Chemical Mutagenesis Strategy using Diethyl Sulphate

Three new (1–3) and 11 known (4–14) C25 steroids with an unusual bicyclo[4.4.1]A/B ring system were isolated by tracing newly produced metabolites in the EtOAc extract of an antitumor mutant AD-1-2 obtained by the diethyl sulphate (DES) mutagenesis of a marine-derived Penicillium purpurogenum G59. H...

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Detalles Bibliográficos
Autores principales: Xia, Ming-Wen, Cui, Cheng-Bin, Li, Chang-Wei, Wu, Chang-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967226/
https://www.ncbi.nlm.nih.gov/pubmed/24633254
http://dx.doi.org/10.3390/md12031545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967226/
https://www.ncbi.nlm.nih.gov/pubmed/24633254
http://dx.doi.org/10.3390/md12031545

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