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A high‐calcium diet failed to rescue an osteopenia phenotype in claudin‐18 knockout mice

We have recently demonstrated that mice with disruption of claudin‐18 (Cldn‐18) gene exhibited osteopenia due to increased bone resorption (BR). In this study, we found that gastric pH was significantly higher in Cldn‐18 knockout (KO) mice compared to heterozygous control mice at 10 weeks of age. To...

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Detalles Bibliográficos
Autores principales: Alshbool, Fatima Z., Alarcon, Catrina, Wergedal, Jon, Mohan, Subburaman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967683/
https://www.ncbi.nlm.nih.gov/pubmed/24744879
http://dx.doi.org/10.1002/phy2.200