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Impaired ability to modulate glomerular filtration rate in aged female sheep following fetal uninephrectomy

Fetal uninephrectomy (uni‐x) results in hypertension at a later age in female than male sheep. We hypothesized that dysregulation of tubular sodium handling contributes to the reduced ability to regulate extracellular fluid (ECF) homeostasis in older females born with a congenital nephron deficit. F...

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Detalles Bibliográficos
Autores principales: Lankadeva, Yugeesh R., Singh, Reetu R., Hilliard, Lucinda M., Moritz, Karen M., Denton, Kate M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967691/
https://www.ncbi.nlm.nih.gov/pubmed/24744887
http://dx.doi.org/10.1002/phy2.208