Cysteine Residues Impact the Stability and Micelle Interaction Dynamics of the Human Mitochondrial β-Barrel Anion Channel hVDAC-2

The anti-apoptotic 19-stranded transmembrane human voltage dependent anion channel isoform 2 (hVDAC-2) β-barrel stability is crucial for anion transport in mitochondria. The role of the unusually high number of cysteine residues in this isoform is poorly understood. Using a Cys-less construct of hVD...

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Detalles Bibliográficos
Autores principales: Maurya, Svetlana Rajkumar, Mahalakshmi, Radhakrishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967697/
https://www.ncbi.nlm.nih.gov/pubmed/24642864
http://dx.doi.org/10.1371/journal.pone.0092183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967697/
https://www.ncbi.nlm.nih.gov/pubmed/24642864
http://dx.doi.org/10.1371/journal.pone.0092183

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