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Modeling Mutual Exclusivity of Cancer Mutations
In large collections of tumor samples, it has been observed that sets of genes that are commonly involved in the same cancer pathways tend not to occur mutated together in the same patient. Such gene sets form mutually exclusive patterns of gene alterations in cancer genomic data. Computational appr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967923/ https://www.ncbi.nlm.nih.gov/pubmed/24675718 http://dx.doi.org/10.1371/journal.pcbi.1003503 |