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TBX3 Regulates Splicing In Vivo: A Novel Molecular Mechanism for Ulnar-Mammary Syndrome

TBX3 is a member of the T-box family of transcription factors with critical roles in development, oncogenesis, cell fate, and tissue homeostasis. TBX3 mutations in humans cause complex congenital malformations and Ulnar-mammary syndrome. Previous investigations into TBX3 function focused on its acti...

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Detalles Bibliográficos
Autores principales: Kumar P., Pavan, Franklin, Sarah, Emechebe, Uchenna, Hu, Hao, Moore, Barry, Lehman, Chris, Yandell, Mark, Moon, Anne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967948/
https://www.ncbi.nlm.nih.gov/pubmed/24675841
http://dx.doi.org/10.1371/journal.pgen.1004247