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Enhanced Protective Efficacy of Nonpathogenic Recombinant Leishmania tarentolae Expressing Cysteine Proteinases Combined with a Sand Fly Salivary Antigen

BACKGROUND: Novel vaccination approaches are needed to prevent leishmaniasis. Live attenuated vaccines are the gold standard for protection against intracellular pathogens such as Leishmania and there have been new developments in this field. The nonpathogenic to humans lizard protozoan parasite, Le...

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Detalles Bibliográficos
Autores principales: Zahedifard, Farnaz, Gholami, Elham, Taheri, Tahereh, Taslimi, Yasaman, Doustdari, Fatemeh, Seyed, Negar, Torkashvand, Fatemeh, Meneses, Claudio, Papadopoulou, Barbara, Kamhawi, Shaden, Valenzuela, Jesus G., Rafati, Sima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967951/
https://www.ncbi.nlm.nih.gov/pubmed/24675711
http://dx.doi.org/10.1371/journal.pntd.0002751