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FAK Acts as a Suppressor of RTK-MAP Kinase Signalling in Drosophila melanogaster Epithelia and Human Cancer Cells

Receptor Tyrosine Kinases (RTKs) and Focal Adhesion Kinase (FAK) regulate multiple signalling pathways, including mitogen-activated protein (MAP) kinase pathway. FAK interacts with several RTKs but little is known about how FAK regulates their downstream signalling. Here we investigated how FAK regu...

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Detalles Bibliográficos
Autores principales: Macagno, Juan Pablo, Diaz Vera, Jesica, Yu, Yachuan, MacPherson, Iain, Sandilands, Emma, Palmer, Ruth, Norman, Jim C., Frame, Margaret, Vidal, Marcos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967952/
https://www.ncbi.nlm.nih.gov/pubmed/24676055
http://dx.doi.org/10.1371/journal.pgen.1004262