Peptide aptamers define distinct EB1- and EB3-binding motifs and interfere with microtubule dynamics

EB1 is a conserved protein that plays a central role in regulating microtubule dynamics and organization. It binds directly to microtubule plus ends and recruits other plus end–localizing proteins. Most EB1-binding proteins contain a Ser–any residue–Ile-Pro (SxIP) motif. Here we describe the isolati...

Descripción completa

Detalles Bibliográficos
Autores principales: Leśniewska, Karolina, Warbrick, Emma, Ohkura, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967968/
https://www.ncbi.nlm.nih.gov/pubmed/24478452
http://dx.doi.org/10.1091/mbc.E13-08-0504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967968/
https://www.ncbi.nlm.nih.gov/pubmed/24478452
http://dx.doi.org/10.1091/mbc.E13-08-0504

Ejemplares similares