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Herp coordinates compartmentalization and recruitment of HRD1 and misfolded proteins for ERAD
A functional unfolded protein response (UPR) is essential for endoplasmic reticulum (ER)-associated degradation (ERAD) of misfolded secretory proteins, reflecting the fact that some level of UPR activation must exist under normal physiological conditions. A coordinator of the UPR and ERAD processes...
Autores principales: | Leitman, Julia, Shenkman, Marina, Gofman, Yana, Shtern, Navit Ogen, Ben-Tal, Nir, Hendershot, Linda M., Lederkremer, Gerardo Z. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967970/ https://www.ncbi.nlm.nih.gov/pubmed/24478453 http://dx.doi.org/10.1091/mbc.E13-06-0350 |
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