ATR Suppresses Endogenous DNA Damage and Allows Completion of Homologous Recombination Repair

DNA replication fork stalling or collapse that arises from endogenous damage poses a serious threat to genome stability, but cells invoke an intricate signaling cascade referred to as the DNA damage response (DDR) to prevent such damage. The gene product ataxia telangiectasia and Rad3-related (ATR)...

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Detalles Bibliográficos
Autores principales: Brown, Adam D., Sager, Brian W., Gorthi, Aparna, Tonapi, Sonal S., Brown, Eric J., Bishop, Alexander J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968013/
https://www.ncbi.nlm.nih.gov/pubmed/24675793
http://dx.doi.org/10.1371/journal.pone.0091222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968013/
https://www.ncbi.nlm.nih.gov/pubmed/24675793
http://dx.doi.org/10.1371/journal.pone.0091222

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