Discovering Aptamers by Cell-SELEX against Human Soluble Growth Factors Ectopically Expressed on Yeast Cell Surface

SELEX, the process of selecting aptamers, is often hampered by the difficulty of preparing target molecules in their native forms and by a lack of a simple yet quantitative assay for monitoring enrichment and affinity of reactive aptamers. In this study, we sought to discover DNA aptamers against hu...

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Detalles Bibliográficos
Autores principales: Meng, Hsien-Wei, Pagano, John M., White, Brian S., Toyoda, Yoshiko, Min, Irene M., Craighead, Harold G., Shalloway, David, Lis, John T., Xiao, Kai, Jin, Moonsoo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968096/
https://www.ncbi.nlm.nih.gov/pubmed/24675636
http://dx.doi.org/10.1371/journal.pone.0093052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968096/
https://www.ncbi.nlm.nih.gov/pubmed/24675636
http://dx.doi.org/10.1371/journal.pone.0093052

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