Roles of Raft-Anchored Adaptor Cbp/PAG1 in Spatial Regulation of c-Src Kinase

The tyrosine kinase c-Src is upregulated in numerous human cancers, implying a role for c-Src in cancer progression. Previously, we have shown that sequestration of activated c-Src into lipid rafts via a transmembrane adaptor, Cbp/PAG1, efficiently suppresses c-Src-induced cell transformation in Csk...

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Detalles Bibliográficos
Autores principales: Saitou, Takashi, Kajiwara, Kentaro, Oneyama, Chitose, Suzuki, Takashi, Okada, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968143/
https://www.ncbi.nlm.nih.gov/pubmed/24675741
http://dx.doi.org/10.1371/journal.pone.0093470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968143/
https://www.ncbi.nlm.nih.gov/pubmed/24675741
http://dx.doi.org/10.1371/journal.pone.0093470

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