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Fusion FISH Imaging: Single-Molecule Detection of Gene Fusion Transcripts In Situ

Double-stranded DNA breaks occur on a regular basis in the human genome as a consequence of genotoxic stress and errors during replication. Usually these breaks are rapidly and faithfully repaired, but occasionally different chromosomes, or different regions of the same chromosome, are fused to each...

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Detalles Bibliográficos
Autores principales: Markey, Fatu Badiane, Ruezinsky, William, Tyagi, Sanjay, Batish, Mona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968151/
https://www.ncbi.nlm.nih.gov/pubmed/24675777
http://dx.doi.org/10.1371/journal.pone.0093488