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U(4) at the 3′ UTR of PB1 Segment of H5N1 Influenza Virus Promotes RNA Polymerase Activity and Contributes to Viral Pathogenicity

The viral RNA-dependent RNA polymerase has been found to contribute to efficient replication in mammalian systems and to the high pathogenicity of H5N1 influenza A virus in humans and other mammals. The terminal untranslated regions of the viral segments perform functions such as polyadenylation and...

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Detalles Bibliográficos
Autores principales: Sun, Wei, Li, Jing, Han, Pengfei, Yang, Yinhui, Kang, Xiaoping, Li, Yuchang, Li, Jiaming, Zhang, Yu, Wu, Xiaoyan, Jiang, Tao, Qin, Chengfeng, Hu, Yi, Zhu, Qingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968160/
https://www.ncbi.nlm.nih.gov/pubmed/24676059
http://dx.doi.org/10.1371/journal.pone.0093366