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Alterations in HIV-1 gp120 V3 Region Are Necessary but Not Sufficient for Coreceptor Switching in CRF07_BC in China

The most predominant HIV-1 strains in China's current epidemic is the Circulating Recombinant Form 07_BC (CRF07_BC). CRF07_BC is mainly considered as a CCR5-tropic (R5) virus, since CXCR4-tropic (X4) viruses have thus far not been found in this subtype, and the molecular determinants of corecep...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Ma, Liying, Wang, Zheng, Wang, Yan, Zhang, Jing, Wang, Haining, Shao, Yiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968174/
https://www.ncbi.nlm.nih.gov/pubmed/24676404
http://dx.doi.org/10.1371/journal.pone.0093426