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Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood

INTRODUCTION: microRNA (miRNA) are small non-coding RNA species that are transcriptionally processed in the host cell and released extracellularly into the bloodstream. Normally involved in post-transcriptional gene silencing, the deregulation of miRNA has been shown to influence pathogenesis of a n...

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Detalles Bibliográficos
Autores principales: Cheng, Lesley, Sharples, Robyn A., Scicluna, Benjamin J., Hill, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968297/
https://www.ncbi.nlm.nih.gov/pubmed/24683445
http://dx.doi.org/10.3402/jev.v3.23743