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Quantification of Process Induced Disorder in Milled Samples Using Different Analytical Techniques
The aim of this study was to compare three different analytical methods to detect and quantify the amount of crystalline disorder/ amorphousness in two milled model drugs. X-ray powder diffraction (XRPD), differential scanning calorimetry (DSC) and Raman spectroscopy were used as analytical methods...
Autores principales: | Zimper, Ulrike, Aaltonen, Jaakko, McGoverin, Cushla M., Gordon, Keith C., Krauel-Goellner, Karen, Rades, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968347/ https://www.ncbi.nlm.nih.gov/pubmed/27721341 http://dx.doi.org/10.3390/pharmaceutics2010030 |
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