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Exogenous expression of marine lectins DlFBL and SpRBL induces cancer cell apoptosis possibly through PRMT5-E2F-1 pathway

Lectins are widely existed in marine bioresources, and some purified marine lectins were found toxic to cancer cells. In this report, genes encoding Dicentrarchus labrax fucose-binding lectin (DlFBL) and Strongylocentrotus purpuratus rhamnose-binding lectin (SpRBL) were inserted into an adenovirus v...

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Detalles Bibliográficos
Autores principales: Wu, Liqin, Yang, Xinyan, Duan, Xuemei, Cui, Lianzhen, Li, Gongchu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968455/
https://www.ncbi.nlm.nih.gov/pubmed/24675921
http://dx.doi.org/10.1038/srep04505