Tumor Lysing Genetically Engineered T Cells Loaded with Multi-Modal Imaging Agents

Genetically-modified T cells expressing chimeric antigen receptors (CAR) exert anti-tumor effect by identifying tumor-associated antigen (TAA), independent of major histocompatibility complex. For maximal efficacy and safety of adoptively transferred cells, imaging their biodistribution is critical....

Descripción completa

Detalles Bibliográficos
Autores principales: Bhatnagar, Parijat, Alauddin, Mian, Bankson, James A., Kirui, Dickson, Seifi, Payam, Huls, Helen, Lee, Dean A., Babakhani, Aydin, Ferrari, Mauro, Li, King C., Cooper, Laurence J. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968458/
https://www.ncbi.nlm.nih.gov/pubmed/24675806
http://dx.doi.org/10.1038/srep04502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968458/
https://www.ncbi.nlm.nih.gov/pubmed/24675806
http://dx.doi.org/10.1038/srep04502

Ejemplares similares