Early specification of CD8(+) T lymphocyte fates during adaptive immunity revealed by single-cell gene expression analyses

T lymphocytes responding to microbial infection give rise to effector cells that mediate acute host defense and memory cells that provide long-lived immunity, but the fundamental question of when and how these cells arise remains unresolved. Here we combine single-cell gene expression analyses with...

Descripción completa

Detalles Bibliográficos
Autores principales: Arsenio, Janilyn, Kakaradov, Boyko, Metz, Patrick J., Kim, Stephanie H., Yeo, Gene W., Chang, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968536/
https://www.ncbi.nlm.nih.gov/pubmed/24584088
http://dx.doi.org/10.1038/ni.2842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968536/
https://www.ncbi.nlm.nih.gov/pubmed/24584088
http://dx.doi.org/10.1038/ni.2842

Ejemplares similares