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Molecular Bases for the Regulation of NKG2D Ligands in Cancer

NKG2D is an activating receptor expressed by NK and T cells primarily involved in the elimination of transformed and infected cells. NKG2D ligands are self-proteins restrictedly expressed in healthy tissues, but induced in response to signaling pathways commonly associated with transformation. Proli...

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Detalles Bibliográficos
Autores principales: Huergo-Zapico, Leticia, Acebes-Huerta, Andrea, López-Soto, Alejandro, Villa-Álvarez, Mónica, Gonzalez-Rodriguez, Ana Pilar, Gonzalez, Segundo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968767/
https://www.ncbi.nlm.nih.gov/pubmed/24711808
http://dx.doi.org/10.3389/fimmu.2014.00106